ISO/IEC 19583-27:2025 PDF

Information technology — Concepts and usage of metadata — Part 27: Mapping between metamodel for computable data registration and bioinformatics analyses by high-throughput sequencing (HTS)

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Title (English):

ISO/IEC 19583-27:2025

Information technology — Concepts and usage of metadata — Part 27: Mapping between metamodel for computable data registration and bioinformatics analyses by high-throughput sequencing (HTS)

Document status:: Active
Format:: Electronic (PDF)
Number of pages:: 50
Publication date:: December 12, 2025
Edition:: ISO/IEC IS 19583 edition 1 version 1
ICS:: 07.080

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Description (English):

This document provides a mapping between the ISO/IEC 11179-34 metamodel for computable data registration and the IEEE 2791 standard for bioinformatics analyses generated by high-throughput sequencing (HTS), to facilitate the production of IEEE 2791 objects from instances of ISO/IEC 11179-34 metamodel and the registration of IEEE 2791 objects as computable data within an MDR conforming to ISO/IEC 11179-34. This document is applicable to those who are submitting data to organizations that require metadata submissions in IEEE 2791 compliant format, as well as those aiming to register IEEE 2791 objects into an MDR that conforms to ISO/IEC 11179-34.

Technical details

Technical committee: ISO/IEC JTC 1/SC 32 - Data management and interchange
SKU: ISO/IEC 19583-27:2025

Abstract

Overview

ISO/IEC 19583-27:2025 defines a formal mapping between two metadata standards used in bioinformatics and metadata registries: the ISO/IEC 11179-34 metamodel for computable data registration and the IEEE 2791 JSON Schema for bioinformatics analyses generated by high‑throughput sequencing (HTS). The standard specifies bidirectional mapping mechanisms to (1) produce IEEE 2791 objects from instances of ISO/IEC 11179-34, and (2) register IEEE 2791 objects as computable data in a Metadata Registry (MDR) conforming to ISO/IEC 11179-34. It supports semantic interoperability, reproducibility, and consistent metadata exchange between research, clinical, and regulatory ecosystems.

Key topics and technical requirements

Mapping mechanisms
- S2M (Schema to Metamodel): maps IEEE 2791 JSON Schema elements into ISO/IEC 11179-34 computable‑data metamodel objects (e.g., spec_version, provenance_domain, io_domain).
- M2S (Metamodel to Schema): maps ISO/IEC 11179-34 computable‑data entries into IEEE 2791 JSON Schema objects.
Data transformation
- Defines transformation rules and types: one‑to‑one, one‑to‑many, many‑to‑one, many‑to‑many (some mappings require human review).
- Covers domain‑specific transformations (spec_version, provenance_domain.review, contributors, pipeline_steps, input/output subdomains, error_domain).
MDR implementation and registration
- Requirements for recording Computable_Data, Supporting_Document, Input_Output_Data, and error metadata within an MDR.
Validation and examples
- Includes mapping tables (e.g., Table 1) and informative Annexes A and B with examples of transforming between IEEE 2791 objects and ISO/IEC 11179-34 computable data.
Normative references
- Relies on ISO/IEC 11179-3, ISO/IEC 11179-33, ISO/IEC 11179-34, and IEEE 2791-2020.

Practical applications and who should use it

Data submitters who must provide HTS bioinformatics metadata in IEEE 2791 format to regulators, repositories, or partners.
MDR administrators and data stewards implementing ISO/IEC 11179-34 to register computable data and enable downstream generation of IEEE 2791 objects.
Bioinformatics platform developers and integrators building exporters/importers between JSON IEEE 2791 artifacts and metadata registries.
Regulatory agencies, pharmaceutical companies, and research consortia seeking reproducible, machine‑readable HTS workflow metadata for review, audit, or data sharing.
Software engineers and ETL specialists responsible for data transformation, validation, and mapping logic between standards.

Related standards

ISO/IEC 11179‑3:2023 (MDR metamodel common facilities)
ISO/IEC 11179‑33:2023 (Metamodel for data set registration)
ISO/IEC 11179‑34:2024 (Metamodel for computable data registration)
IEEE 2791‑2020 (Bioinformatics Analyses Generated by HTS; JSON Schema)

Keywords: ISO/IEC 19583-27:2025, metadata mapping, computable data registration, IEEE 2791, ISO/IEC 11179-34, MDR, HTS, bioinformatics, JSON Schema, data transformation, S2M mapping, M2S mapping.

Related standards

Standards mentioned in the description

Abstract

Overview

Key topics and technical requirements

Mapping mechanisms
- S2M (Schema to Metamodel): maps IEEE 2791 JSON Schema elements into ISO/IEC 11179-34 computable‑data metamodel objects (e.g., spec_version, provenance_domain, io_domain).
- M2S (Metamodel to Schema): maps ISO/IEC 11179-34 computable‑data entries into IEEE 2791 JSON Schema objects.
Data transformation
- Defines transformation rules and types: one‑to‑one, one‑to‑many, many‑to‑one, many‑to‑many (some mappings require human review).
- Covers domain‑specific transformations (spec_version, provenance_domain.review, contributors, pipeline_steps, input/output subdomains, error_domain).
MDR implementation and registration
- Requirements for recording Computable_Data, Supporting_Document, Input_Output_Data, and error metadata within an MDR.
Validation and examples
- Includes mapping tables (e.g., Table 1) and informative Annexes A and B with examples of transforming between IEEE 2791 objects and ISO/IEC 11179-34 computable data.
Normative references
- Relies on ISO/IEC 11179-3, ISO/IEC 11179-33, ISO/IEC 11179-34, and IEEE 2791-2020.

Practical applications and who should use it

Data submitters who must provide HTS bioinformatics metadata in IEEE 2791 format to regulators, repositories, or partners.
MDR administrators and data stewards implementing ISO/IEC 11179-34 to register computable data and enable downstream generation of IEEE 2791 objects.
Bioinformatics platform developers and integrators building exporters/importers between JSON IEEE 2791 artifacts and metadata registries.
Regulatory agencies, pharmaceutical companies, and research consortia seeking reproducible, machine‑readable HTS workflow metadata for review, audit, or data sharing.
Software engineers and ETL specialists responsible for data transformation, validation, and mapping logic between standards.

Related standards

ISO/IEC 11179‑3:2023 (MDR metamodel common facilities)
ISO/IEC 11179‑33:2023 (Metamodel for data set registration)
ISO/IEC 11179‑34:2024 (Metamodel for computable data registration)
IEEE 2791‑2020 (Bioinformatics Analyses Generated by HTS; JSON Schema)

Keywords: ISO/IEC 19583-27:2025, metadata mapping, computable data registration, IEEE 2791, ISO/IEC 11179-34, MDR, HTS, bioinformatics, JSON Schema, data transformation, S2M mapping, M2S mapping.

ISO/IEC 19583-27:2025 PDF

Technical details

Abstract

Overview

Key topics and technical requirements

Practical applications and who should use it

Related standards

Related standards

Abstract

Overview

Key topics and technical requirements

Practical applications and who should use it

Related standards

Related standards

Information technology — Metadata registries (MDR) — Part 3: Metamodel for registry common facilities

Information technology — Metadata registries (MDR) — Part 33: Metamodel for data set registration

Information technology — Metadata registries (MDR) — Part 34: Metamodel for computable data registration

Information technology — Metadata registries (MDR) — Part 3: Registry metamodel and basic attributes

Tracked Changes. Information technology. Metadata registries (MDR). Metamodel for data set registration.