SIST EN ISO 10298:2020/A1:2022 PDF

Gas cylinders - Gases and gas mixtures - Determination of toxicity for the selection of cylinder valve outlets - Amendment 1 (ISO 10298:2018/Amd 1:2021)

Title (English):

SIST EN ISO 10298:2020/A1:2022

Gas cylinders - Gases and gas mixtures - Determination of toxicity for the selection of cylinder valve outlets - Amendment 1 (ISO 10298:2018/Amd 1:2021)

Document status:: Active
Format:: Electronic (PDF)
Number of pages:: 7
Publication date:: October 20, 2022
ICS:: 23.020.35
Technical committee:: TLP - Pressure vessels

Document language:

enru

Delivery time:1–7 days

Price:44 €

Description (English):

This document lists the best available acute-toxicity data of gases taken from a search of the current literature to allow the classification of gases and gas mixtures for toxicity by inhalation. Scope of amendment Changes to formula in clause 4.3

Technical details

SKU: SIST EN ISO 10298:2020/A1:2022

Abstract

Overview

EN ISO 10298:2020/A1:2022 (ISO 10298:2018/Amd 1:2021) is an amendment to the international standard for gas cylinders that provides authoritative guidance on the determination of toxicity for gases and gas mixtures to support the selection of cylinder valve outlets. The standard compiles best-available acute inhalation toxicity data from the literature so that gases and mixtures can be classified for toxicity by inhalation and appropriate valve outlet types can be selected to reduce handling and exposure risks.

Key topics and requirements

Purpose: Use acute-toxicity data to classify gases/gas mixtures by inhalation toxicity for safe cylinder valve outlet selection.
Data basis: Best-available LC50 (lethal concentration) values from current literature; emphasis on acute inhalation toxicity.
Mixture calculation: Amendment 1 updates the mixture toxicity formula in clause 4.3. The revised formula for estimating the mixture LC50 is:
- 1/LC50 = Σi (Ci / LC50i)
- where Ci is the mole fraction of the i‑th toxic component and LC50i is the lethal concentration of that component (applicable when LC50i

Related standards

Mentioned in the description and other SIST standards

Overview

Key topics and requirements

Purpose: Use acute-toxicity data to classify gases/gas mixtures by inhalation toxicity for safe cylinder valve outlet selection.
Data basis: Best-available LC50 (lethal concentration) values from current literature; emphasis on acute inhalation toxicity.
Mixture calculation: Amendment 1 updates the mixture toxicity formula in clause 4.3. The revised formula for estimating the mixture LC50 is:
- 1/LC50 = Σi (Ci / LC50i)
- where Ci is the mole fraction of the i‑th toxic component and LC50i is the lethal concentration of that component (applicable when LC50i

SIST EN ISO 10298:2020/A1:2022 PDF

Technical details

Abstract

Overview

Key topics and requirements

Related standards

Abstract

Overview

Key topics and requirements

Related standards

Gas cylinders — Gases and gas mixtures — Determination of toxicity for the selection of cylinder valve outlets

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