Overview
ISO 11023:1999 is an internationally recognized standard developed by the International Organization for Standardization (ISO). It specifies a method for determining the glycyrrhizic acid content in liquorice extracts derived from Glycyrrhiza glabra L. utilizing high-performance liquid chromatography (HPLC). The standard provides a consistent, reliable technique for analytical laboratories, quality controllers, and manufacturers involved in the production and evaluation of liquorice extracts. Note that this method is not applicable to raw or ground liquorice root; it is specifically intended for processed liquorice extracts.
Key Topics
- Glycyrrhizic Acid Determination: Central to the standard is the accurate quantification of glycyrrhizic acid, the key active compound in liquorice extracts.
- HPLC Analysis: The method relies on high-performance liquid chromatography, a widely used analytical technique offering precision and reproducibility in quantifying specific compounds.
- Sample Preparation: Specifies requirements for the preparation of analytical standard and sample solutions, including the composition and handling of solvents and reagents.
- Quality of Reagents: Emphasizes the use of reagents and solvents of recognized analytical or HPLC grade to ensure data validity.
- Calibration and Calculation: Provides procedures for calibration curve establishment, chromatogram analysis, and the formula for calculating glycyrrhizic acid content by mass.
- Reporting Results: Outlines the necessary components of a comprehensive test report, including details for sample identification and test conditions.
Applications
ISO 11023:1999 is widely applicable across various sectors of the food, flavor, and pharmaceutical industries, particularly where liquorice extract quality and authenticity are critical:
- Quality Control in Manufacturing: Manufacturers of liquorice-based products can employ this standard to verify glycyrrhizic acid concentrations and ensure product consistency.
- Regulatory Compliance: Compliance with ISO 11023:1999 helps producers meet regulatory standards concerning product purity and labeling, especially in markets with strict food safety requirements.
- Research and Development: Analytical laboratories utilize this method for research purposes, including product development and comparative studies.
- Import/Export Verification: Authorities can use the standard to validate the quality of liquorice extracts in international trade.
By ensuring reliable, comparable results, ISO 11023:1999 supports transparent, high-quality processes in the global liquorice extract supply chain.
Related Standards
- ISO 8432: Essential oils – Analysis by high-performance liquid chromatography – General method. This standard provides general guidance on HPLC techniques relevant to essential oils and is referenced in ISO 11023:1999.
- Other ISO Standards for Food Additives: Many ISO publications address analytical methods and quality control of food ingredients and natural products, reinforcing reliability across the industry.
Practical Value
Implementing ISO 11023:1999 offers significant benefits, including:
- Reliable Testing: Laboratories and producers can trust their results when measuring glycyrrhizic acid, thanks to the detailed, step-by-step HPLC procedure.
- International Recognition: Adoption of ISO 11023:1999 facilitates acceptance of test results and products in global markets.
- Consistent Quality: Following standardized methods helps ensure that liquorice extract products meet defined quality criteria every time.
This standard is a vital tool for anyone involved in the supply, manufacture, analysis, or regulation of liquorice extracts, supporting both commercial interests and consumer safety by ensuring the accurate measurement of glycyrrhizic acid content.
Open preview (PDF)Liquorice extracts (Glycyrrhiza glabra L.) — Determination of glycyrrhizic acid content — Method using high-performance liquid chromatography
